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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b72076c248db2fc66ca3525284a5b1cd2f516febe9b8713a30dd8dd6ead8a951' 
  AND token = 'irI72Vvjym2LhV2OqS4cAX5Ab+4+eaqV8LTVewVOUoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}