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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '19f568490fd36fb011f4c2eebfdd2a47cdad99fa48757a5ab08b2c7cce535580' 
  AND token = 'UG9Pb+R9uODR+kHWcnimG1uekHfuc2n+VXaWwiGEp8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}