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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd3e0fb358454b2120592704f1f8dac0552bd09d7cc4630e45499c347c3052343' 
  AND token = 'oGlYDWAr+ROCmEfyMpF0p5WSe5iIwkP3n4SwtFZvZQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}