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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4f8fdd5134ed55c3a3b40a6c29bffa558cab251828ad0cc8bc695cfe2f21c0cc' 
  AND token = '11qCK+F7HbdOjacv+mzor8mUY89GlsTdspvuH1wNZ60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}