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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e6686e7ccf696df79c869800490752a7e70a153c3678cddd58e102b200b301d3' 
  AND token = '3AublJmZS5JfkNnI7rsP4+/4NdynRSLg6cjWVs78D80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}