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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1ae63b1780f2c502fa080316927635be162808b61e0a506891ba3e8607f2cbf0' 
  AND token = 'vpyX0QfYgxizSvsLWY6FwHziP2xu0WP5gly2dW1akMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}