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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8125168641bc5459339c5db6d3f3443e90ceca9b1581169facce426d857ebc3c' 
  AND token = 'xS7OAPGQQIHpo335Mw4eeg0fM13MD/16qvjS5NmvFuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}