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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '289e757de8645f695eea2ff7c83338da0d877fb641268f183c33347bc4ec2ecc' 
  AND token = 'O6xxN+18Q02xJqDRZUNz/qca72xmYAsVDoFxTRbYJ/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}