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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '85d6e00534fbac33d38aea9b4ba461c4a3c027fb8a2adfec691872b4676f6c5d' 
  AND token = 'zLQMnbw+e+V6plBztPUM9RCgMvOfOkdCsbQ8pQmnBd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}