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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c6a8838b213628da8e55a970d62d9254e7f6223dcb5662c8b42e2aa08d596a80' 
  AND token = 'SvUwLVk61PE8wW7wsX/NmCZDjzS2407y0fkaGv8E7Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}