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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6bdf500d8ea74c4bd96cc56dbd0ae8743a9355660d8ffa987048b7096e476208' 
  AND token = 's2rKleR6Ht2kr5jNCNCoWJe/U3F4mFiBywuiizlQo4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}