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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '622beea5dd6b27a9e7f9f8205d951dc160927262de51c65fdcb29f45fd55b9a1' 
  AND token = 'MUeG4fIhEmVI+uAzYdxhgkbCXAwpxNwLE1GJcg12LFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}