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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7a5d24e09ae05e344dd708e4b85276b31167d746c469c8241d2b96306e4c4287' 
  AND token = 'RQHzY72iDY3Z2DVqN+ToFC67PGb4PUSCZSCTwmZwGOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}