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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f4ce2fdd3020c7c59524e726effbebffa9a9b3c1dc3966b7fcf2d61d06364566' 
  AND token = 'xKW6Aa99i/53zRLedCjA5YgBNukuc3ZxhFCeRyrm7xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}