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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e8ed3c98a96c30f89797b9e45188606145b12982a8a136457b63b7fb50864fcf' 
  AND token = 'YI2HcivMRZ6tKKBw5n19scFYIVKaP6TVAi9Y86/xarY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}