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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a99d7a023d13c0730ebdf239d2a6750549ee24a7104e7993b0575cd12204d921' 
  AND token = '59X5JjU/MEJyMEj/jSpSunaz9nlIzusOdBm4geFKZw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}