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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '486c2fbdffaaa26b9f491175576e75c052dd582e6f12eb1d8accb0c1aaefa8ef' 
  AND token = 'tUzDLnO1X/ok9M56zQFc0kzOYcfchOUdUa1Bje7Iqcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}