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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4209f445d261fcbb6981006fa573576a8cc1dd01aaaf67ba1d38ec5981695fbd' 
  AND token = '3rFsVdFAfR/fQfjo8AWF0+mA4NxJdPJCf9xbTfnlfDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}