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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '91fa2bae3a8a5921e0bac641a47e30b4158abada67e6be822ec90c6b2c3a1845' 
  AND token = 'K7RZlVrI+FFxr1eoqQTd+c6hvTKkuTUKHkEbbSDYmdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}