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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8ac6b577064c8cb49f80b456f973dc734754e12b6f58b9003576fa0eb116f1ef' 
  AND token = 'sPDYW/IQ6VGBrTYN9uglbtHSXBjn3MleUSDMIit2A74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}