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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '257d58e4799caee3e7878e813ae0a36c757a05aeb8b1eebffdeaad425d392678' 
  AND token = 'gw40NA3RS+OONzzwvG+ce7cPIKXz1eVZHR7nZ+akyDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}