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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '44c0378bc78bced1c13a70f2f4a993255b09309b5827ec7fbecc1df17b0a8c07' 
  AND token = 'uLtXGDsqwc5nNcLO11P9jEB7UX4DHsWIlRtLhgdH0iU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}