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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4c145caddbaf186644b352379f2fd9b7c57faadddc1595dde91b0e2e1904181d' 
  AND token = 'FXxBzibIaH+cDyb0zqR6s439buQMXjKDoXGIS3XVyWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}