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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '439183678133feeebef3ed4cd17bbe37bc248bf98bf1b075b413e79703a53545' 
  AND token = 'GEt5ikOhg+wB8iWN7DXBcoAHjss/9Kndd0NDzfNmRFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}