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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2407c6143f67c75c7da77d61042c43216ae17bcd21eebf667c66028c238b3b2c' 
  AND token = 'Qj0sgdov6vF3RNNr9+j5PfyI308dk25BGMGjMWHtieQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}