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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1017dea61ffde0c3828d3fd38c2bc3bd1280b87c2497b0e6031834a699f42510' 
  AND token = 'tNOU1Duuzxydey7UePmTl+wnx5h5WPyJRGTupV7p30I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}