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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e4aad0dd1e20fb113b464a49af772436ddd33530c4f160cad49dd7c1e42e4af9' 
  AND token = 'cOvSTJiRjNplTuWa71rpF+6eg+/NysR9vTAGO+l+ZwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}