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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2162ff8951e3fe911295612a31692bb7cd144a0d63265b3d1e8dc97a935213b4' 
  AND token = 'HQ8feFiBvNiXPUNiVbiWgGD/nHP6jgR744PeovsE9QA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}