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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a4521798f967cadc7468ea9b61eabe1e7f9c845e8984ad7bb6843455201ca5ed' 
  AND token = 'HHQEHbte349GsVA7fzyf0fBHVZ6U5LTpaxb/T62eo4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}