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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '412c02284b113ff8555d6cadf9d5452b8a203f5de05b0c2ec18ebac19bcdc542' 
  AND token = '/7EA3WhuLTuvPfTWm29btiMjcaV4zMKgC7ZTFpCNae0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}