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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'df21c56f9f21e9f8d5d54d740fbe254a74f4ab04154bb5a4b11de314b988918a' 
  AND token = '7uWR/j4YmQdkr+bLEcCQyuh7KomqepgpWwsHqPEvb4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}