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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2fcb27e89fe91ca7f8e351d7078d0ff75579a351fa8c267b015f3d23ca1f4010' 
  AND token = 'HWcXO2WLWLGs80mSr9KNL7IotzKy4S4/8L/bh1fjqa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}