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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3f8cf9564d0eb53feb2777e46ff46842b262830438f581732f2044ad1ffe07f1' 
  AND token = 'npnMBuVkQxXlOl4j079N9keo031Clwas9myf8N+eljQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}