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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8e6489c0e11af3a3aa8629aea662c3ae858942c09ad36df3849b69f94222aae7' 
  AND token = 'pNis256y5ugRqHkZVdMTbTItTPRXrLeIgUb6zRD4jos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}