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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e889465ba4a84dbc9e9a0366d51e6e41f012b41ff92103462224d9b2e9f5e2c7' 
  AND token = 'GpDbaxN9802IUWDBcvUDRpBXnUZO2uTaH4TR5YYL9v8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}