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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '01455e67fa3b0f7f352388fb720f72886452efe5db88f4489602b65695f84e4a' 
  AND token = 'afr2xYoefT4s5QxTjRPZ59A1HiAI9ZAeBE+AdPcRQY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}