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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd9b6aae822eed5045baab323e2b3a559eb35dbd95d0df048e59dcd427aec7249' 
  AND token = 'HOmYGNxL1MyXvqN/q2iSk53pBAt+b9XdvpWosCpTlK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}