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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'af78e318dfea25e786ef941e2e342b98d8efce0125fff99abd0f651d18719211' 
  AND token = 'FGYMNy8KbXAeSRiVZxTIo2/Bbwq25HULn1V3Qfm77Rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}