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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4ca86b0e4587fe811b0fc2f5ff7979eea65fbb01e82c1c14977a388dbbed4e69' 
  AND token = 'NTUS36Q8ey8vEchGBXZkfDEWxTKCXWlZC9/DOFzVKUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00125

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}