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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '37b25ec214bd9a44b93b4a472a0b01e99fcb661515106e93b2e44b7c219d4d03' 
  AND token = 'eowkKpEdWCpohxzGYANP/tSW5YwQ0HwVdsj31+m9oLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}