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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cd52e6df72863f6c4988c911d81706b34ca0bb8c29f9a00f3c86f00269c79a06' 
  AND token = 'SkNWIrgbkzH5Gy67e8EEkbQKvjpC4UiFn0KN71biXZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}