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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0ce0e78032fcc70c4f3fac602d700eb8965462fdf51b037532c910c29746d4e0' 
  AND token = 'a2W4DHeyGGjHeSbRRvOispa5XQmEsTG1g/dFk3UhjL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}