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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '763ec4d45513711aa8c9e137dc37ecc718e5b4851c6daf441a7542ca613d6cec' 
  AND token = 'wOBDAdRqrNDmW2RNIqP3pSjTf6s9e+xR+8qwDN3hj+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}