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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0f5c4b12c36c5602762afb36d7fd436f79d447b494b3a7fe41c51a607fe9e557' 
  AND token = 'DtjUYnBNEfzbUyGRMdABlkpJAO+Uu5pD9pbiM2EXtvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}