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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0280dcf163f37e56733628e7b2af36f579c6989745bd4469b64367df674b75cc' 
  AND token = '2wk582fRDIYuyPnJUjuMkJ3jpN8fUSzTkjfgLUHz3co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}