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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fe23a4d5561f1a12314c641e4a14b972ad04c32710f5562f71b7deaa871abc74' 
  AND token = 'GM/rLr+p5kCcHIrnV4T/LhyHyRejOhD0YAnWsYp2qnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}