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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c5346441e843996e65e6210fa8b80f863774c87c81a94f565b74cce887351663' 
  AND token = '3uxytkJ3T8BxBkbBMkLabnScEkQD/8pQ8GEN0rRvxO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}