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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b6a6e78d5d959eb91496f1cc089c27d85111800d261ef70f0e198fed25eee1e2' 
  AND token = 'cNCPtG7YmPkPESF+rMwmz5cacJEUOOtHsMCqnlFKeJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}