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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e5ef5010d9a628c802b86e1ee2a2a2dd0e147cc5ab2510b019dd0623c622ddee' 
  AND token = 'FjTh2d8X3okrdfcwBgqeXGt4d4P0gEQ7/XoAEJpS8kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}