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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1c55c08bf6429b6a71c24bf0a5c30558405029bfe222c571db2e292f9a7f0a8b' 
  AND token = '9B6P/NdisTBQKP41yTK8Itq1Ic1Gwc32VtcQ+TjHo6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}